METFORMIN Research Paper Example | Topics and Well Written Essays - 500 words

METFORMIN - Research Paper Example But the widest indication of the drug is for the treatment of type 2 diabetes. The drug is given to control the blood glucose levels of patients in the normal range so that the proper bodily functions are retained and the problems of the nervous system; cardiovascular system and the renal system are avoided in the diabetic patients. The drug has an added benefit since it has been proved that the drug does not result in reduction of the blood glucose level below normal and the patient does not experience episodes of hypoglycemia. It also does not lead to increased weight in the patient who takes this drug. This is the reason that it is preferably prescribed to the diabetic patients. The drug works via various mechanisms which include increasing the sensitivity of the cells towards their response to insulin by increasing the uptake of glucose by the cells. It further promotes the intracellular metabolism of the glucose as well. Furthermore, it leads to a reduction in the amount of hepa tic glucose as well as renal glucose that is released into the bloodstream by means of reducing the amount of its production in these organs. In a similar manner, it also reduces the absorption of glucose from the intestines. The main side effects of the drug include gastrointestinal problems. These include diarrhea, vomiting, nausea as well as feeling of uneasiness in the abdomen. It has also been proven that metformin causes a decrease in the absorption of vitamin B12 by the intestine and hence it can lead to reduction in its levels. The gastrointestinal symptoms generally subside. Thus, it has been seen that the drug does not lead to very serious side effects.